
Ketamine Treatment in Orillia
What is Ketamine
Ketamine, originally developed in 1962 as a safer alternative to phencyclidine, serves as a dissociative anesthetic for surgical sedation and pain management. Its applications have expanded to include depression treatment in recent years, showcasing its versatility in medical practice.
What is Ketamine for Depression?
Ketamine therapy for depression involves the administration of ketamine, typically via intravenous infusion or nasal spray, under medical supervision. Unlike traditional antidepressants, which often take weeks to show effects, ketamine can bring about rapid relief from depressive symptoms, sometimes within hours. Its mechanism of action in treating depression is not fully understood, but it is believed to involve the modulation of certain neurotransmitters in the brain, such as glutamate and serotonin.
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Who do we treat at Orillia Ketamine Clinic
At Orillia Ketamine Clinic, we specialize in addressing treatment-resistant depression (TRD), encompassing conditions such as major depressive disorder, depressive phases of bipolar 1 and bipolar 2, as well as suicidal ideation. Additionally, individuals with other mood disorders like PTSD, OCD, and anxiety may also receive treatment if their symptoms are part of a depressive episode. It’s imperative that patients presently experiencing depression to be eligible for our services.
At Orillia Ketamine Clinic we administer ketamine via nasal spray, under medical supervision.
What is the response rate for ketamine therapy in treatment resistant depression?
The response rate for ketamine therapy in treatment-resistant depression (TRD) varies among individuals and studies, but it’s generally reported to be significant. Clinical trials have shown that a substantial proportion of patients with TRD experience rapid and significant improvements in depressive symptoms after receiving ketamine treatment. Response rates often range from 50% to 70%, with some studies reporting even higher rates. However, it’s essential to note that not all patients respond to ketamine therapy, and the duration of response can vary. Some may experience a temporary relief of symptoms, while others may have a more sustained improvement
Who might not be suitable for ketamine treatment?
Individuals with certain medical conditions or circumstances may not be suitable candidates for ketamine treatment. Contraindications for ketamine therapy may include:
- Uncontrolled or severe hypertension (high blood pressure).
- History of psychosis or schizophrenia.
- Active substance abuse or dependence.
- Severe liver or kidney disease.
- Recent history of heart attack or stroke.
- Certain medications or drug interactions.
- Allergy or hypersensitivity to ketamine or related compounds.
It’s crucial for individuals considering ketamine therapy to undergo a comprehensive medical evaluation to determine if they have any contraindications or potential risks associated with the treatment. Always consult with a qualified healthcare provider to assess your suitability for ketamine therapy based on your individual medical history and current health status.
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What to Expect After Ketamine Treatment?
After a ketamine treatment, individuals may experience various sensations and effects. These can include:
- Relief: Many people report feeling a sense of relief from depressive symptoms shortly after the treatment.
- Light-headedness: Ketamine can cause feelings of light-headedness or dizziness, particularly during and immediately after the infusion.
- Euphoria: Some individuals may experience a temporary sense of euphoria or heightened mood following the treatment.
- Relaxation: Ketamine can induce a state of relaxation or calmness in some individuals.
- Disassociation: Ketamine is a dissociative anesthetic, so some people may experience a temporary disconnection from their surroundings or sense of detachment from reality.
- Increased Sensitivity: Sensory perceptions may be altered, with sounds, colors, or other stimuli appearing more intense or vivid.
- Fatigue: Ketamine treatments can sometimes lead to feelings of tiredness or drowsiness after the effects wear off.
It’s important to note that individual experiences can vary, and some people may not feel any immediate effects after a ketamine treatment. Additionally, the duration and intensity of these effects can differ from person to person. Always discuss any concerns or questions about post-treatment experiences with your healthcare provider.
One of the key advantages of intranasal ketamine is its ease of administration, which can be performed in a clinical setting or even at home under the guidance of a healthcare provider. This method allows for greater flexibility and convenience compared to IV ketamine infusions, which typically require administration by a healthcare professional in a clinical setting.
While intranasal ketamine shows promise as a treatment option for individuals who have not responded to traditional antidepressant medications, further research is needed to fully understand its long-term efficacy and safety profile. As with any medical treatment, it’s essential to consult with a qualified healthcare provider to determine the most appropriate approach based on individual needs and medical history.
As with any medical treatment, it’s essential to consult with a qualified healthcare provider to determine the most appropriate treatment approach based on individual circumstances and medical history.
Do I need a Doctor’s referral to get ketamine treatment?
You must obtain a referral from either a general practitioner (GP) or a psychiatrist to access Orillia Ketamine Clinic. You can find a copy of the referral form below.
Appointment Cancellation:
Any member who cancels an appointment after the specified cut-off time outlined in the policy below.
Late Arrival: Any member who arrives at the clinic 15 minutes past the scheduled appointment time.
No Show: Any member who fails to attend their ketamine therapy appointment at Orillia Ketamine Clinic.
Our Policy:
Appointment Cancellation Notification Deadline: Please contact us at 705-327-7070 or by email, by noon, the business day before your scheduled appointment, to inform us of any changes or cancellations. For example, call the office by noon on Thursday to reschedule an appointment set for Friday or call our office by noon on Friday to cancel a Monday appointment.
Ketamine Appointments: Failure to notify cancellation before noon of the preceding business day will result in a $200 charge for the missed appointment.
Important Note: Please aim to arrive 10 to 15 minutes before your scheduled appointment time. If you are 10 or more minutes late, the appointment may be canceled and rescheduled, with cancellation fees applicable.
Repeated missed appointments may lead to termination of your treatment eligibility at Orillia Ketamine Clinic
Contact Us

The Brain Health Centre
17 Colborne St E, Unit 104, Orillia, ON L3V 3L3
Phone: 705-327-7070
Fax: 705-327-7474
If you’re faxing from a doctors office or a pharmacy, please use this number: 1-877-503-6584